Neurobiology of Disease Distinct and Non-Redundant Roles of Microglia and Myeloid Subsets in Mouse Models of Alzheimer’s Disease

Alexander Mildner,1* Bernhard Schlevogt,2* Katrin Kierdorf,1,6* Chotima Böttcher,3 Daniel Erny,1 Markus P. Kummer,4 Michael Quinn,3 Wolfgang Brück,2 Ingo Bechmann,5 Michael T. Heneka,4 Josef Priller,3* and Marco Prinz1* 1Department of Neuropathology, University of Freiburg, D-79106 Freiburg, Germany, 2Department of Neuropathology, Universitätsmedizin Göttingen, D-37099 Göttingen, Germany, 3Department of Neuropsychiatry and Laboratory of Molecular Psychiatry, BCRT and NeuroCure, CharitéUniversitätsmedizin Berlin, D-10117 Berlin, Germany, 4Department of Neurology, Rheinische Friedrich-Wilhelms-Universität, D-53127 Bonn, Germany, 5Institute of Anatomy, University of Leipzig, D-04103 Leipzig, Germany, and 6Faculty of Biology, University of Freiburg, D-79104 Freiburg, Germany